Scholars and researchers in the field of health and allied sciences are working on bringing treatment to help in mitigating the spread of the COVID-19. Since the outbreak of the global pandemic, the focus is on clinical evaluation, treatment, and diagnosis of the COVID-19. But so far, no drug has been proved to be safe and effective for treating COVID-19.
Among the few emergency use treatment options, Convalescent Plasma Therapy for COVID-19 is the one that has been used by the doctors to treat individual hospitalized patients affected with COVID global pandemic.
What is Convalescent Plasma Therapy?
Convalescent plasma therapy is an old way of treating infectious diseases by supplying antibodies to patients. During this therapy, plasma is infused into patients to provide a source of antibodies against SARS-CoV-2.
Plasma is a colourless liquid component of blood that contains proteins, hormones, sugar, potassium, vitamins, sodium, calcium, clotting factors.
The blood plasma therapy COVID is not new in the field of medical science. The plasma of the patients who have been recovered from COVID contains antibodies called convalescent plasma. It is infused in patients with severe COVID-19 to fight the virus. In comparison to vaccine convalescent plasma therapy works differently. On receiving the vaccine, the immune system creates its antibodies to the microbe you are being protected.
How did the idea of implementing this therapy come? Who took the initiative to use CPT or passive antibody therapy?
Well, physiologist Emil von Behring and bacteriologist Kitasato Shibasaburou emphasized using antibodies present in serum to treat the bacterial infection diphtheria. It was in the late 19th century when doctors used passive antibody therapy to fight against diseases like pneumonia, meningitis, and measles.
The plasma therapy has been successful in various viral illnesses such as Ebola, diphtheria, the 2009 influenza A, and 2003 SARS-CoV.
How effective is convalescent plasma therapy for COVID-19?
As per the study, CPT is not a win-win treatment for COVID-19 as there are ongoing studies to check the effectiveness of this treatment.
The limited clinical information reveals that CPT may prove to be an effective treatment option for COVID-19 patients, but further studies are required to confirm its efficacy.
Regarding the side effects associated with convalescent plasma therapy, plasma transfusions are considered safe, but some there are some side effects reported by the doctors. Fever, allergy, bronchospasm, acute lung injury, and in rare cases, the transmission of infectious diseases is probably to happen with CPT. Despite these effects, transfusion of plasma can help patients with chronic medical conditions like diabetes, heart diseases, and also to those with a weakened immune system.
People who have been recovered from COVID-19 are eligible for blood donations with specific conditions to save the life of ill patients.