With COVID-19 cases continuing to grow, researchers worldwide are putting their best efforts to develop vaccines and treatments to reduce the damage caused.
Some of the earliest treatments will probably be drugs that are already approved or used to treat other medical conditions.
In a breakthrough for COVID-19 treatment, researchers in the UK have claimed that the standard steroid drug dexamethasone can reduce the mortality rate in COVID-19 patients.
As per the recent study by the UK, Dexamethasone is the first Lifesaving Coronavirus drug that could save lives. The study reveals that one in three deaths prevented among patients on ventilators, and one in five could be the ratio for those on oxygen.
Announced on June 16, the preliminary results about deemed Dexamethasone as a lifesaving drug for COVID-19. Researchers at the University of Oxford said that the recovery trial clarifies that treatment with Dexamethasone will help reduce the number of deaths in COVID-19 patients.
As Dr. Tedros Adhanom Ghebreyesis (WHO director-general) said, the contribution of the University of Oxford and many hospitals in the UK has brought the first treatment that can reduce the number of deaths in COVID affected patients requiring oxygen or ventilator support.
What is Dexamethasone?
Dexamethasone is a steroid not meant for people with mild symptoms but can prove lifesaving for those with severe symptoms. The drug is already in use to treat arthritis, lupus, psoriasis, ulcerative colitis, and breathing disorders and added to treating COVID-19 moderate to severe cases.
Dexamethasone possesses anti-inflammatory and immunosuppressant properties, used to treat the diseases caused when the body’s immune system attacks the body. For Coronavirus affected patients, the infection results in inflammation, which can be fatal in some cases if the body goes into overdrive.
The drug recommended to use for adults only and not for pregnant women or breastfeeding. Avoid Dexamethasone’s if you have a fungal infection anywhere in your body.
What does the dexamethasone trial results indicate?
For the clinical trial, Oxford researchers tested about 2,000 COVID patients, and then the results were compared to more than 4,000 patients who not given the drug. The data reveals the cut down of the death rate from 40 percent to 28 percent for the patients on ventilators. And, for the patients, need oxygen. A reduction from 25 percent to 20 percent observed.
Being affordable and globally available, Dexamethasone gives effective treatment for the COVID-19 patients on ventilators or are on oxygen, said by Martin Landray (Oxford University Professor).
Researchers feel a lot of uncertainty about the safety and effectiveness of the corticosteroids in COVID-19. The Corticosteroids used for syndromes that are strictly related to COVID-19, including SARS, MERS, influenza, and pneumonia.